Julia Bihorac

Sustained learned immunosuppression could not prevent local allergic ear swelling in a rat model of contact hypersensitivity

This study shows that learned immunosuppression in a rat model of contact hypersensitivity could not prevent local allergic ear swelling, suggesting local allergic reactions may be too strong to respond to learned immunosuppressive effects.

Constitutive activity of the inhibitory G protein pathway mediated by non-visual opsin Opn7b reduces cFos activity in stress and fear circuits and modulates avoidance behavior

This study shows that Opn7b, a constitutively active GPCR, reduces cFos expression and modulates avoidance behavior in mice by activating the Gi/o pathway in specific brain regions.