MicrobiologybioRxivPreprint
Phage RyR-domain proteins degrade ADPR-based immune signals and fuel NAD synthesis
Mercedes Rivera, Renee B. Chang, Colin M. Lewis…·Philip J. Kranzusch
This study identifies RyDEP as an enzyme that degrades 2'cADPR and 3'cADPR immune signals, inactivating bacterial defense and restoring NAD+.
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