TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles
Sönke Rudnik, Chun Hei Li, Dieter-Christian Gottschling, Alexander Veh, Daniel J. Barbosa, Julia Richter, Stijn Stroobants, Bjoern Schuster, Inken M. Beck, Radislav Sedláček, Robert Häsler, Mara Riechmann, Frank Döring, Paul Säftig, Rudi D’Hooge, , Markus Daμμe
This study shows TMEM55B and TMEM55A regulate lysosome distribution in neurons by affecting motor protein transport, with TMEM55B specifically promoting anterograde transport of LAMP1-positive organelles.
bioRxiv · Oct 28, 2026 · PreprintCell Biology