Ex vivo delivery of regulatory T cells for control of alloimmune priming in the donor lung
E. Miyamoto, A. Takahagi, A. Ohsumi, T. Martinu, D. Hwang, K. Boonstra, B. Joe, M. Juan Umana, K. Bei, D. Vosoughi, M. Liu, M. Cypel, S. Keshavjee, S. C. Juvet
This study shows that ex vivo delivery of regulatory T cells to donor lungs before transplantation can suppress alloimmune responses and improve lung graft outcomes in a rat model.
bioRxiv · Feb 7, 2021Immunology