No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice
V. Iyer, K. Boroviak, M. Thomas, B. Doe, E. Ryder, D. Adams
The paper assesses CRISPR-Cas9 off-target effects in gene-edited mice using trio sequencing and finds no unexpected off-target activity.
bioRxiv · Feb 9, 2018Bioengineering