BiochemistrybioRxiv
Identification of Small Molecule Modulators of Diguanylate Cyclase by FRET-based High-Throughput-Screening
M. Christen, C. Kamischke, H. D. Kulasekara…·S. I. Miller
This study identifies small molecule modulators of the diguanylate cyclase DgcA using FRET-based screening and structure-activity analysis, revealing diverse chemical scaffolds with inhibitory or activating effects.
DOI 10.1002/cbic.201800593