Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children
A. X. Han, Z. C. Felix Garza, M. R. A. Welkers, R. M. Vigeveno, N. D. Tran, T. Q. M. Le, Q. T. Pham, D. T. Dang, T. N. A. Tran, M. T. Ha, T. H. Nguyen, Q. T. Le, T. H. Le, T. B. N. Hoang, K. Chokephaibulkit, , C. A. Russell
This study examines within-host evolutionary dynamics of seasonal and pandemic influenza A viruses in young children, finding that nonsynonymous mutations decrease over time in A/H1N1pdm09 but increase in A/H3N2 due to mutation-selection balance.
bioRxiv · Mar 20, 2021Microbiology