C. A. Russell

This paper develops a mini-genome assay using negative-sense RNA to study SARS-CoV-2 replication inhibitors and mutations, offering high sensitivity and ease of use in standard labs.

This study examines within-host evolutionary dynamics of seasonal and pandemic influenza A viruses in young children, finding that nonsynonymous mutations decrease over time in A/H1N1pdm09 but increase in A/H3N2 due to mutation-selection balance.

The paper shows that the timing mismatch between virus growth and antibody selection limits antigenic evolution within hosts, explaining global selectivity and local neutrality in influenza.