A Universal Stress Protein upregulated by hypoxia may contribute to chronic lung colonisation and intramacrophage survival in cystic fibrosis.
A. O'Connor, R. Berisio, M. Lucey, K. E. Schaffer, S. McClean
This study identifies distinct roles of two upregulated universal stress proteins in Burkholderia cenocepacia during chronic CF lung infection, showing USP76 supports macrophage survival while USP92 enhances virulence.
bioRxiv · Oct 3, 2020Microbiology