Author

S. McClean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

R. Berisio· 2 shared A. O'Connor· 1 shared J. Tomas-Cortazar· 1 shared K. E. Schaffer· 1 shared L. Ardill· 1 shared M. A. Valvano· 1 shared M. Lucey· 1 shared M. Romano· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

R. Berisio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BpOmpW Antigen Stimulates the Necessary Immune Correlates of Protection Against Melioidosis

J. Tomas-Cortazar, S. McClean

This study shows that BpOmpW antigen induces strong immune responses in mice, including IFN-γ production and T cell activation, suggesting it may be a protective vaccine candidate for melioidosis.

bioRxiv · May 16, 2021 · PreprintImmunology

A Universal Stress Protein upregulated by hypoxia may contribute to chronic lung colonisation and intramacrophage survival in cystic fibrosis.

A. O'Connor, R. Berisio, M. Lucey, K. E. Schaffer, S. McClean

This study identifies distinct roles of two upregulated universal stress proteins in Burkholderia cenocepacia during chronic CF lung infection, showing USP76 supports macrophage survival while USP92 enhances virulence.

bioRxiv · Oct 3, 2020Microbiology

The DNA mimic protein BCAS0292 is involved in the regulation of virulence of Burkholderia cenocepacia

R. Dennehy, S. Dignam, S. McCormack, M. Romano, Y. Hou, L. Ardill, M. V. Whelan, Z. Drulis-Kawa, T. O Croinin, M. A. Valvano, R. Berisio, S. McClean

This study identifies BCAS0292 as a DNA-mimic protein in B. cenocepacia that regulates virulence and gene expression by altering DNA topology.

bioRxiv · Aug 6, 2020Microbiology