Author

R. Berisio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

M. Romano· 2 shared S. McClean· 2 shared A. O'Connor· 1 shared A. Ruggiero· 1 shared C. K. Cote· 1 shared D. H. McNitt· 1 shared F. Squeglia· 1 shared G. Hu· 1 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

M. Romano

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Universal Stress Protein upregulated by hypoxia may contribute to chronic lung colonisation and intramacrophage survival in cystic fibrosis.

A. O'Connor, R. Berisio, M. Lucey, K. E. Schaffer, S. McClean

This study identifies distinct roles of two upregulated universal stress proteins in Burkholderia cenocepacia during chronic CF lung infection, showing USP76 supports macrophage survival while USP92 enhances virulence.

bioRxiv · Oct 3, 2020Microbiology

Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei

M. E. Grund, S. J. Choi, D. H. McNitt, M. Barbier, G. Hu, P. R. LaSala, C. K. Cote, R. Berisio, S. Lukomski

This study identifies Bucl8 as a unique outer membrane component of a tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei, showing its role in fusaric acid resistance, fibrinogen binding, and growth.

bioRxiv · Sep 18, 2020Microbiology

The DNA mimic protein BCAS0292 is involved in the regulation of virulence of Burkholderia cenocepacia

R. Dennehy, S. Dignam, S. McCormack, M. Romano, Y. Hou, L. Ardill, M. V. Whelan, Z. Drulis-Kawa, T. O Croinin, M. A. Valvano, R. Berisio, S. McClean

This study identifies BCAS0292 as a DNA-mimic protein in B. cenocepacia that regulates virulence and gene expression by altering DNA topology.

bioRxiv · Aug 6, 2020Microbiology

An engineered stable mini-protein to plug SARS-Cov2 Spikes

M. Romano, A. Ruggiero, F. Squeglia, R. Berisio

The paper engineers a stable mini-protein that binds to SARS-CoV-2 Spike protein's RBD to block ACE2 interaction, showing nanomolar affinity and potential as an antiviral tool.

bioRxiv · Apr 29, 2020 · PreprintBiophysics