PALS1 is a key regulator of the lateral distribution of tight junction proteins in renal epithelial cells.
A.-C. Groh, S. Kleimann, P. Nedvestky, M. Behrens, A. Moeller-Kerutt, V. Hoeffken, S. Ghosh, U. Hansen, M. P. Krahn, A. Ludwig, K. Ebnet, H. Pavenstaedt, T. Weide
This study shows that PALS1 regulates tight junction protein localization at bicellular junctions in renal epithelial cells, preventing increased paracellular permeability.
bioRxiv · Apr 27, 2023Cell Biology