Author

K. Elenius

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

I. Paatero· 3 shared A. Jokilammi· 2 shared K. M. Vaparanta· 2 shared A. Padzik· 1 shared A. Vogt· 1 shared C. Sahlgren· 1 shared D. Chakroborty· 1 shared J. A. M. Merilahti· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

I. Paatero

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phosphoproteomic analysis reveals the diversity of signaling behind ErbB inhibitor-induced phenotypes

K. M. Vaparanta, A. Jokilammi, J. Merilahti, J. Orling, N. Virtanen, C. Sahlgren, K. Elenius, I. Paatero

This study uses phosphoproteomic analysis in zebrafish to show that ErbB inhibitors affect multiple signaling pathways, leading to similar physiological phenotypes.

bioRxiv · Mar 12, 2024Cell Biology

Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis

M. Momeny, M. Tienhaara, D. Chakroborty, M. Sharma, R. Varjus, J. Merisaari, A. Padzik, A. Vogt, I. Paatero, K. Kurppa, K. Elenius, T. D. Laajala, J. Westermarck

This study identifies DUSP6 as a driver of HER2 inhibitor tolerance through the Neuregulin/HER3 axis by analyzing the transcriptional changes during the DTP-DTEP transition in HER2+ breast cancer cells.

bioRxiv · Jun 14, 2023 · PreprintCancer Biology

STAT5b is a key effector of NRG-1/ERBB4-mediated cardiomyocyte growth

K. M. Vaparanta, A. Jokilammi, I. Paatero, J. A. M. Merilahti, J. Heliste, K. A. Hemanthakumar, R. Kivelä, K. K. Alitalo, P. Taimen, K. Elenius

This study identifies STAT5b as a critical mediator of NRG-1/ERBB4-induced cardiomyocyte growth and shows its dysregulation in cardiac hypertrophy.

bioRxiv · Oct 5, 2022 · PreprintCell Biology