A novel humanized mouse model to study mucosal HIV-1 transmission and prevention
K. Vanshylla, K. Held, T. Eser, H. Gruell, K. Jain, D. Weiland, J. Muench, B. Gruettner, C. Geldmacher, F. Klein
This paper introduces a novel humanized mouse model, CD34T+, which is highly permissive to mucosal HIV-1 infection and can be prevented by broadly neutralizing antibodies.
bioRxiv · Aug 31, 2020Immunology