Exponential Growth of Glioblastoma In Vivo Driven by Rapidly Dividing and Outwardly Migrating Cancer Stem Cells
L. Buchauer, M. A. Khan, Y. Zhuo, C. Shao, P. Zou, W. Feng, M. Qian, G. Bekki, C. Bunne, A. Neuerburg, A. A. Acikgöz, M. Tomaschko, Z. Zhu, H. Alter, K. Hartmann, , H.-K. Liu
This study identifies that glioblastoma grows exponentially due to symmetric divisions of brain tumor stem cells (BTSCs) accumulating at the tumor rim.
bioRxiv · Aug 5, 2019 · PreprintCancer Biology