Author

K. Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

C. Ibar· 2 shared E. Kirichenko· 2 shared A. Han· 1 shared B. Keepers· 1 shared C. Rauskolb· 1 shared E. Enners· 1 shared K. Fleisch· 1 shared M. C. Ibar Valenzuela· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

C. Ibar

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3 papers

Recent·Most cited

Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains

C. Rauskolb, A. Han, E. Kirichenko, C. Ibar, K. Irvine

The paper investigates the distinct functions of Drosophila Ajuba LIM protein's LIM domains in regulating Hippo signaling and cell shape through in vivo and in vitro experiments.

bioRxiv · May 18, 2022 · PreprintCell Biology

TRIP6 is required for tension at adherens junctions

S. Venkatramanan, M. C. Ibar Valenzuela, K. Irvine

This study shows TRIP6 is required for LIMD1 localization to adherens junctions and for maintaining tension at these junctions by organizing F-actin and recruiting Vinculin and VASP.

bioRxiv · Apr 19, 2020Cell Biology

Tension-dependent regulation of mammalian Hippo signaling through LIMD1

C. Ibar, E. Kirichenko, B. Keepers, E. Enners, K. Fleisch, K. Irvine

This study identifies a biomechanical pathway regulating mammalian Hippo signaling through tension-dependent LIMD1-mediated recruitment and inhibition of Lats kinases at adherens junctions.

bioRxiv · Dec 22, 2017Cell Biology