Author

K. Jooss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

N. L. Kelleher· 3 shared L. F. Schachner· 2 shared M. A. Cheek· 2 shared M. J. Meiners· 2 shared M.-C. Keogh· 2 shared S. A. Howard· 2 shared A. Akoopie· 1 shared A. Lee· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

N. L. Kelleher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A self-amplifying mRNA COVID-19 vaccine drives potent and broad immune responses at low doses that protects non-human primates against SARS-CoV-2

A. R. Rappaport, S.-J. Hong, C. D. Scallan, L. Gitlin, A. Akoopie, G. R. Boucher, M. Egorova, J. A. Espinosa, M. Fidanza, M. A. Kachura, A. Shen, G. Sivko, A. Van Abbema, R. L. Veres, K. Jooss

This paper develops a self-amplifying mRNA vaccine that induces strong immune responses in mice and non-human primates, offering protection against SARS-CoV-2 at low doses.

bioRxiv · Nov 8, 2021 · PreprintImmunology

Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis - Top-Down Mass Spectrometry (nCZE-TDMS)

K. Jooss, L. F. Schachner, R. Watson, Z. B. Gillespie, S. A. Howard, M. A. Cheek, M. J. Meiners, J. D. Licht, M.-C. Keogh, N. L. Kelleher

The paper introduces nCZE-TDMS, a platform for separating and characterizing nucleosomes, histone subunits, and PTMs, and applies it to study histone modifications in cell lines with altered NSD2/MMSET expression.

bioRxiv · Nov 25, 2020Biochemistry

Standard Procedures for Native CZE-MS of Proteins and Protein Complexes up to 800 kDa

K. Jooss, J. P. McGee, R. D. Melani, N. L. Kelleher

The paper provides standard operating procedures for native capillary electrophoresis mass spectrometry (nCZE-MS) to improve reproducibility and data quality for large proteins and complexes.

bioRxiv · Nov 2, 2020Biochemistry

Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS

L. F. Schachner, K. Jooss, M. A. Morgan, A. Piunti, M. J. Meiners, A. Lee, J. O. Kafader, M. Iwanaszko, M. A. Cheek, J. M. Burg, S. A. Howard, M.-C. Keogh, A. Shilatifard, N. L. Kelleher

The paper introduces Nuc-MS, a method to analyze protein composition of whole nucleosomes, revealing specific histone variants and modifications associated with oncogenic states.

bioRxiv · Sep 8, 2020Biochemistry