Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum
M. S. Bulloch, L. K. Huynh, K. Kennedy, J. E. Ralton, M. J. McConville, S. A. Ralph
This study shows that apicoplast-derived isoprenoids are essential for GPI anchor biosynthesis in Plasmodium falciparum, which is critical for parasite egress and invasion.
bioRxiv · Feb 14, 2024 · PreprintCell Biology