Metabolic connections between folate and peptidoglycan pathways in Pseudomonas aeruginosa inform rational design of a dual-action inhibitor
L. N. Yaeger, D. Sycantha, P. Luong…·L. L. Burrows
This study identifies metabolic links between folate and peptidoglycan pathways in Pseudomonas aeruginosa and uses these insights to design a dual-action inhibitor that overcomes antibiotic resistance.