Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania
P. C. Casarotto, C. Biojone, K. Montezuma, F. Q. Cunha, S. R. L. Joca, E. Castren, F. S. Guimaraes
This study shows that NOS2 knockout mice exhibit increased barbering behavior and repetitive movements, linked to altered NMDA receptor levels and neuronal morphology, suggesting a role for NOS2 in striatal motor regulation.
bioRxiv · Nov 9, 2016Animal Behavior & Cognition