K. Okubo

The decision of male medaka to mate or fight depends on two complementary androgen signaling pathways

This study shows that male medaka use two distinct androgen receptor pathways to decide whether to mate or fight, with Ara promoting aggression and Arb promoting courtship.

Comprehensive analysis of gene regulatory dynamics, fitness landscape, and population evolution during sexual reproduction

The paper analyzes gene regulatory dynamics and fitness landscapes in two-gene networks to study population evolution during sexual reproduction.

Allogeneic testes transplanted into partially castrated adult medaka (Oryzias latipes) can produce donor-derived offspring by natural mating over a prolonged period

This study shows that allogeneic testes can engraft in partially castrated medaka without immunosuppression and produce donor-derived offspring through natural mating.

Heterosis Related to Fitness and Phenotypic Variance in the Evolution of Diploid Gene Regulatory Network

This study numerically evolves diploid gene regulatory networks to show that heterozygote populations have higher fitness and lower phenotypic variance than homozygotes, linking heterosis to noise robustness and overdominance.

Evolution of Mendelian dominance in gene regulatory networks associated with phenotypic robustness

This paper shows that Mendelian dominance evolves in gene regulatory networks through complex genotype-phenotype interactions, increasing phenotypic robustness to noise and genetic differences.