Oncogenic signaling alters cell shape and mechanics to facilitate cell division under confinement.
H. K. Matthews, S. Ganguli, K. Plak, A. V. Taubenberger, M. Piel, J. Guck, B. Baum
This study shows that oncogenic Ras-ERK signaling changes cell mechanics and division behavior under confinement, aiding mitotic rounding and chromosome segregation.
bioRxiv · Mar 9, 2019Cell Biology