KMT2D regulates thymic egress by modulating maturation and integrin expression
S. J. Potter, L. Zhang, M. Kotliar, Y. Wu, C. Schafer, K. Stefan, L. Boukas, D. Qu'd, O. Bodamer, B. N. Simpson, A. Barski, A. W. Lindsley, H. T. Bjornsson
This study shows that KMT2D regulates thymic egress by affecting maturation and integrin expression in T cells, leading to immune dysfunction in Kabuki syndrome type 1.
bioRxiv · Oct 4, 2022 · PreprintImmunology