Author

K. Stepniak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Kaminska· 3 shared B. Wojtas· 3 shared M. J. Dabrowski· 3 shared A.-J. Roura· 2 shared B. Gielniewski· 2 shared M. Draminski· 2 shared M. Jardanowska· 2 shared A. Dziedzic· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

B. Kaminska

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3 papers

Recent·Most cited

Comprehensive analysis of the transcription factor REST regulatory networks in IDH-mutant and IDH-wild type glioma

M. Perycz, M. J. Dabrowski, M. Jardanowska, A.-J. Roura, B. Gielniewski, K. Stepniak, M. Draminski, B. Kaminska, B. Wojtas

This study identifies differences in REST regulatory networks between IDH-mutant and IDH-wild type gliomas, highlighting distinct gene expression control mechanisms.

bioRxiv · Jul 28, 2022 · PreprintCancer Biology

Regulatory networks driving expression of genes critical for glioblastoma are controlled by the transcription factor c-Jun and the pre-existing epigenetic modifications.

A.-J. Roura, P. Szadkowska, K. Poleszak, M. J. Dabrowski, A. Ellert-Miklaszewska, K. Wojnicki, I. A. Ciechomska, K. Stepniak, B. Kaminska, B. Wojtas

The paper identifies c-Jun as a key transcription factor regulating genes critical for glioblastoma, with DNA methylation modulating its activity in GBM cells.

bioRxiv · Jul 18, 2022Cancer Biology

Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

K. Stepniak, M. A. Machnicka, J. Mieczkowski, A. Macioszek, B. Wojtas, B. Gielniewski, S. K. Krol, R. Guzik, M. J. Dabrowski, M. Draminski, M. Jardanowska, I. Grabowicz, A. Dziedzic, H. Kranas, K. Sienkiewicz, , B. Wilczynski

The paper maps chromatin accessibility and regulatory elements in human gliomas to identify new epigenetic mechanisms driving cancer progression.

bioRxiv · Mar 20, 2020Cancer Biology