Author

K. Takenaga

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Pharmacology & Toxicology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Okamoto· 1 shared C. Sumi· 1 shared H. Tanaka· 1 shared J.-I. Hayashi· 1 shared K. Hirota· 1 shared K. Nishi· 1 shared M. Kusunoki· 1 shared T. Adachi· 1 shared

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2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Okamoto

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivNov 16, 2017

Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner

C. Sumi, A. Okamoto, H. Tanaka…·K. Hirota

This study shows propofol causes metabolic reprogramming and cell death by impairing mitochondrial function, specifically complexes I and III, and this effect is exacerbated by preexisting mitochondrial dysfunction.

DOI 10.1371/journal.pone.0192796

humanmetabolomics

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