A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
R. Fan, C. Sportelli, Y. Lai, S. Salehe, J. Pinnell, J. R. Richardson, S. Luo, K. Tieu
This study shows that partial Drp1 knockout enhances autophagy flux without affecting mitochondrial function, revealing a distinct protective mechanism against manganese toxicity.
bioRxiv · Jun 29, 2023Cell Biology