K. Trang

Identification of intestinal mediators of Caenorhabditis elegans DBL-1/BMP immune signaling shaping gut microbiome composition

The paper identifies five intestinal DBL-1/BMP signaling targets that regulate Enterobacteriaceae abundance in C. elegans, suggesting they are part of an antibacterial response.

Microbiome remodeling through bacterial competition and host behavior enables rapid adaptation to environmental toxins.

This study shows that gut microbiomes can help animals adapt to environmental toxins through bacterial competition and host behavior, but this adaptation may come with trade-offs.