Author

S. Hammond

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Lee· 2 shared E. Clancy-Thompson· 2 shared P. Wiklund· 2 shared R. M. de Real· 2 shared S. Kim-Schulze· 2 shared A. Charap· 1 shared A. Demetriou· 1 shared A. M. Farkas· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

B. Lee

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Author profile →

4 papers

Recent·Most cited

The HLA-E/NKG2A axis identifies a therapeutic vulnerability in BCG-unresponsive bladder cancer

Bérengère Salomé, Haocheng Yu, Daniel L Ranti, Ying‐Chih Wang, C. Bieber, Pierre‐Etienne Gabriel, Igor Duquesne, Trine Strandgaard, B. Hug, Sean Houghton, Hiranmayi Ravichandran, Elliot Merritt, S. Bang, A. Demetriou, Z. Li, , Amir Horowitz

This study identifies the HLA-E/NKG2A axis as a therapeutic target in BCG-unresponsive bladder cancer by showing its role in immune evasion and impaired effector cell function.

bioRxiv · Sep 2, 2024 · PreprintCancer Biology

Identification of intestinal mediators of Caenorhabditis elegans DBL-1/BMP immune signaling shaping gut microbiome composition

K. Trang, B. Pees, S. Karimzadegan, R. Bodkhe, S. Hammond, M. Shapira

The paper identifies five intestinal DBL-1/BMP signaling targets that regulate Enterobacteriaceae abundance in C. elegans, suggesting they are part of an antibacterial response.

bioRxiv · Oct 26, 2023 · PreprintMicrobiology

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

B. Salome, J. P. Sfakianos, J. Daza, A. Charap, C. Hammer, R. Banchereau, A. M. Farkas, D. Geanon, G. Kelly, R. M. de Real, B. Lee, K. G. Beaumont, S. Shroff, Y. S. A. Wang, Y.-C. Wang, , Mariath

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

bioRxiv · Mar 4, 2022 · PreprintImmunology

Evolution Of Coprophagy And Nutrient Absorption In A Cave Salamander

D. Soares, R. Roenfeldt, S. Hammond, M. E. Slay, D. B. Fenolio, M. L. Niemiller

This study investigates diet breadth expansion in grotto salamanders, finding coprophagy occurs but is insufficient for nutrition, suggesting behavioral adaptation precedes physiological changes.

bioRxiv · Apr 3, 2017Animal Behavior & Cognition