Tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex
C. Z. Koo, N. Harrison, P. J. Noy, J. Szyroka, A. L. Matthews, H.-E. Hsia, S. A. Mueller, J. Tushaus, J. Goulding, K. Willis, C. Apicella, B. Cragoe, E. Davis, M. Keles, A. Malinova, , M. G. Tomlinson
The paper identifies Tspan15 as a critical partner of ADAM10, showing their interaction and functional synergy in proteolytic activity.
bioRxiv · Oct 11, 2019Cell Biology