Cardiolipin, and not monolysocardiolipin, preferentially binds to the interface of Complexes III and IV
R. A. Corey, N. Harrison, P. J. Stansfeld, M. S. P. Sansom, A. L. Duncan
This study shows that cardiolipin, not monolysocardiolipin, preferentially binds to the interface of mitochondrial supercomplexes containing Complexes III and IV, suggesting MLCL disrupts supercomplex stability in Barth syndrome.
bioRxiv · Jul 21, 2022Biochemistry