Author

K.-C. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

P. Ghosh· 2 shared V. Nizet· 2 shared C. Michaud· 1 shared C. Plaisier· 1 shared E. Kuliyev· 1 shared H.-C. Huang· 1 shared J. Rousseau· 1 shared M. Mungaray· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

P. Ghosh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development

H.-C. Huang, T.-Y. Wang, J. Rousseau, M. Mungaray, C. Michaud, C. Plaisier, Z. B. Chen, K.-C. Wang

This paper develops a biomimetic nanodrug targeting YAP/TAZ in atherosclerotic plaques, showing reduced plaque development in mice with minimal off-target effects.

bioRxiv · Apr 24, 2023 · PreprintBioengineering

An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37

P. Kolesinski, K.-C. Wang, Y. Hirose, V. Nizet, P. Ghosh

The paper reveals how M87 protein from Streptococcus pyogenes interacts with LL-37 by unfolding its coiled coil to expose a hydrophobic core, neutralizing the antimicrobial peptide.

bioRxiv · Jan 11, 2022Microbiology

Design of a Streptococcus pyogenes M protein immunogen to elicit M type cross-reactivity

K.-C. Wang, E. Kuliyev, V. Nizet, P. Ghosh

The paper designs an M protein immunogen that elicits cross-reactivity against multiple M types by targeting a conserved 3D pattern in the hypervariable region.

bioRxiv · Dec 7, 2021Immunology