The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis
M. Woodall, A.-M. Cujba, K. B. Worlock, K.-M. Case, T. Masonou, M. Yoshida, K. Polanski, N. Huang, R. G. Lindeboom, L. Mamanova, L. Bolt, L. Richardson, S. Ellis, M. Palor, T. Burgoyne, , C. M. Smith
The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.
bioRxiv · Jan 16, 2023 · PreprintCell Biology