A. Pinto

High-fat and high-carbohydrate diets worsen the mouse brain susceptibility to damage produced by enterohemorrhagic Escherichia coli Shiga toxin 2

This study shows that high-fat and high-carbohydrate diets exacerbate brain damage caused by Shiga toxin 2 in mice, with the combined diet causing the most severe neurological impairments.

CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

This study shows that CD4+ and CD8+ T cells are necessary to prevent SARS-CoV-2 persistence in the nasal compartment but not in the lungs.

Metatranscriptomic analysis reveals synergistic activities of comammox and anammox bacteria in full-scale attached growth nitrogen removal system.

The paper investigates how dissolved oxygen affects the synergistic nitrogen removal by comammox and anammox bacteria in wastewater treatment systems.

Comammox bacterial preference for urea influences its interactions with aerobic nitrifiers.

This study investigates how nitrogen source and loading conditions affect interactions between comammox bacteria and aerobic nitrifiers in continuous flow reactors, finding that urea promotes comammox abundance while ammonia inhibits it.

The emergence of goblet inflammatory or ITGB6hi nasal progenitor cells determines age-associated SARS-CoV-2 pathogenesis

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

Co-occurrence and cooperation between comammox and anammox bacteria in a full-scale attached growth municipal wastewater treatment process.

The paper reports co-occurrence and cooperation between comammox and anammox bacteria in a full-scale wastewater treatment system, showing dissolved oxygen-dependent nitrogen loss.

Comammox Nitrospira bacteria outnumber canonical nitrifiers irrespective of nitrogen source and availability

The paper investigates nitrifier population dynamics in drinking water biofilters, finding comammox bacteria dominate over canonical nitrifiers regardless of nitrogen source.

Increased transmission of SARS-CoV-2 lineage B.1.1.7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape

This study shows that SARS-CoV-2 variant B.1.1.7 does not replicate better in airway cells or escape antibodies, suggesting its increased transmissibility is due to other factors.

Cognitive deficits found in a pro-inflammatory state are independent of ERK 1/2 signaling in the murine brain hippocampus treated with Shiga toxin 2 from enterohemorrhagic Escherichia Coli

This study shows that Stx2 induces cognitive deficits and inflammation in the hippocampus independently of ERK 1/2 signaling, while LPS requires ERK 1/2 for NF-kB activation.

Detecting and Quantitating Low Fraction DNA Variants with Low-Depth Sequencing

This paper introduces mBDA, a method to detect low-frequency DNA variants with low-depth sequencing, and applies it to find tumor heterogeneity in melanoma samples.

First description of a herpesvirus infection in genus Lepus

The paper describes the first identification of a herpesvirus in Iberian hares, which circulates asymptotically and is phylogenetically related to bat and rodent herpesviruses.

Plagiarism in Brazil: A perspective of 25,000 PhD holders across the sciences

This study surveys 25,157 Brazilian PhD holders across sciences to assess plagiarism perceptions, finding shared principles aligning with Merton's observations on scientific discovery.

Long solids retention times and attached growth phase favor prevalence of comammox bacteria in nitrogen removal systems.

This study identifies conditions favoring comammox bacteria in wastewater treatment systems and develops a qPCR assay to quantify them.

Disinfectant residuals in drinking water systems select for mycobacterial populations with intrinsic antimicrobial resistance.

This study shows that disinfectant residuals in drinking water systems are linked to higher prevalence of antimicrobial resistance genes in nontuberculous mycobacteria.