R. E. Hynds

The paper identifies lymphoproliferative B cells in NSCLC PDX models and develops a tool for generating pathology overview figures.

This paper develops a bioreactor-based whole-organ lung model to study viral infections and demonstrates its use for testing antiviral drugs like Remdesivir.

The study identifies age-related differences in nasal epithelial cell responses to SARS-CoV-2 infection, showing distinct progenitor cell dynamics in children and elderly.

This study examines how well PDX models capture intratumour heterogeneity in NSCLC, finding that most models originate from a single subclone but regional models can capture diversity.

The paper profiles lung immune cells during development using scRNAseq and identifies IL-1β's role in driving epithelial progenitor differentiation.

This study identifies key transcriptional pathways in IPF fibroblastic foci using RNA-seq and bioinformatics, highlighting the TSC2/RHEB axis as a potential therapeutic target for fibrosis.

The paper compares airway epithelial cells from children and adults, finding intrinsic differences in transcriptional profiles and regenerative capacity.

The paper develops a high-content screening method using differentiated respiratory epithelium from PCD patients to evaluate readthrough therapies for rare respiratory diseases.

The paper investigates immune surveillance in pre-invasive squamous cell lung cancer, finding that regressive lesions have more immune infiltration and distinct molecular profiles compared to progressive lesions.