Author

K. A. Lazarus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. C. Orr· 2 shared R. E. Hynds· 2 shared S. M. Janes· 2 shared A. Laali· 1 shared A. Pennycuick· 1 shared B. E. Hartley· 1 shared C. Al Yaghchi· 1 shared C. Denais· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

J. C. Orr

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Author profile →

3 papers

Recent·Most cited

A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence

J. C. Orr, A. Laali, P. F. Durrenberger, K. A. Lazarus, M.-B. El Mdawar, S. M. Janes, R. E. Hynds

This paper develops lentiviral reporter constructs to quantitatively monitor airway epithelial cell differentiation using bioluminescence in vitro.

bioRxiv · Feb 9, 2024Cell Biology

Cell-intrinsic differences between human airway epithelial cells from children and adults

E. F. Maughan, R. E. Hynds, A. Pennycuick, E. Nigro, K. H. C. Gowers, C. Denais, S. Gomez-Lopez, K. A. Lazarus, J. C. Orr, D. R. Pearce, S. E. Clarke, D. D. H. Lee, M. N. J. Woodall, T. Masonou, K.-M. Case, , S. M. Janes

The paper compares airway epithelial cells from children and adults, finding intrinsic differences in transcriptional profiles and regenerative capacity.

bioRxiv · Apr 20, 2020Cell Biology

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma

K. A. Lazarus, F. Hadi, E. Zambon, K. Bach, M.-F. Santolla, J. K. Watson, L. L. Correia, M. Das, R. Ugur, S. Pensa, L. Becker, L. S. Campos, G. Ladds, P. Liu, G. Evan, , W. T. Khaled

This study identifies BCL11A as an oncogene in lung squamous cell carcinoma, showing its interaction with SOX2 to regulate epigenetic factors and demonstrating potential therapeutic targets.

bioRxiv · Nov 22, 2017Cancer Biology