BiochemistrybioRxivPreprint
Functional Locality-Aligned Learning Reveals Structure-Function Causality in Enzyme Kinetics
Hao Zhang, He Zhang, Miao Kang…·Nanning Zheng
This paper introduces EnzymePlex, a framework that improves enzyme kinetic parameter prediction by aligning structural and functional representations, achieving better generalization and mechanistic insights.
DOI 10.64898/2026.03.04.709726