Author
University of Pittsburgh
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Collin R. Diedrich, Tara Rutledge, Janelle L. Gleim…·Philana Ling Lin
This study shows that antiretroviral treatment (ART) does not prevent extrapulmonary tuberculosis in SIV/Mtb co-infected macaques, despite suppressing SIV replication.
Pauline A Maiello, Collin R. Diedrich, Tara W. Rutledge…·Philana Ling Lin
The paper investigates TB relapse in a macaque model, finding that complete sterilization protects against relapse but PET CT cannot predict it, and that Mtb dissemination originates from both lung and lymph nodes.
Christian T. Michael, Maral Budak, Pauline A Maiello…·Denise E. Kirschner
The paper simulates TB antibiotic regimens in a computational model to show rankings are influenced by spatial scale, detection limit, and initial bacterial burden.
Shu Wang, Amy J. Myers, Edward B. Irvine…·Douglas A. Lauffenburger
The paper uses Markov Fields to integrate multi-modal immune data from vaccinated macaques, identifying critical immune interactions and predicting perturbation effects.
Joshua D. Bromley, Sharie Keanne C. Ganchua, Sarah K. Nyquist…·JoAnne L. Flynn
The paper shows that CD4+ T cells reduce inflammation and disease severity during Mtb reinfection by reprogramming CD8+ T cells and innate immune cells.