Author

Karen Mitchell

Manchester Academic Health Science Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Advait Veeraghanta· 1 shared Basudha BasuiD· 1 shared Bernard D. KeavneyiD· 1 shared Charlie F RowlandsiD· 1 shared Colin A. JohnsoniD· 1 shared Dale W. MaxwelliD· 1 shared Dapeng WangiD· 1 shared David J. SmithiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Advait Veeraghanta

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1 paper

Recent·Most cited

The RNA splicing factor PRPF8 is required for left-right organiser cilia differentiation and determination of cardiac left-right asymmetry via regulation of Arl13b splicing

Fangfei Jiang, Michael Boylan, Dale W. Maxwell, Wasay Mohiuddin Shaikh Qureshi, Charlie F Rowlands, Gennadiy Tenin, Karen Mitchell, Louise A. Stephen, Elton J. R. Vasconcelos, Dapeng Wang, Tong Chen, Junzhe Zha, Jingshu Liu, Nouf J. Althali, Dragoș-Vasile Leordean, , Kathryn E. Hentges

This study identifies PRPF8 as essential for left-right organiser cilia function and cardiac asymmetry by regulating ARL13B splicing in mice and zebrafish.

bioRxiv · May 22, 2025 · PreprintDevelopmental Biology