Elton J. R. Vasconcelos

This study uses direct RNA sequencing to show that Leishmania infection remodels the host m6A epitranscriptome, affecting immune and metabolic transcripts.

This study identifies conventional dendritic cells type 1 (cDC1s) as critical for anti-tumor immunity in brain metastases, showing their unique role in promoting CD8+ T cell responses and enhancing immunotherapy efficacy.

This study demonstrates that AAV-mediated PRPF31 gene therapy restores splicing homeostasis and rescues RP11 phenotypes in patient-derived RPE and retinal organoids.

The paper develops a bovine endometrial organoid model to study hormone responsiveness and conceptus-maternal interactions, identifying differentially expressed genes and biological processes.

This study analyzes acetylation across 48 organisms, identifying conserved acetylation sites and their roles in metabolic processes and stress response.

This study identifies PRPF8 as essential for left-right organiser cilia function and cardiac asymmetry by regulating ARL13B splicing in mice and zebrafish.

The paper examines translational activity of 80S monosomes in different Drosophila tissues, finding that head and embryo monosomes are active while testis and ovary monosomes are inactive.

This study shows that sirtuins in Aspergillus fumigatus are important for virulence and pathogenesis, with AfSirE deletion reducing virulence and altering protein acetylation and gene expression.

The paper investigates how endometrial biosensor capability is influenced by miRNA cargo in conceptus-derived extracellular vesicles during peri-implantation, showing differential miRNA effects on endometrial gene expression.

The paper uses an endometrium-on-a-chip system to show that changes in glucose and insulin concentrations alter the transcriptome and secretome of endometrial cells in vitro.

The paper identifies lncRNAs that interact with the translation machinery during neuronal differentiation and shows some produce peptides that affect neurite length.