Cell BiologybioRxivPreprint
An aged human bone marrow mesenchymal niche causes impaired function of human hematopoietic stem cells under regeneration-induced stress
Ani Grigoryan, Ruba Abdelrahman, Wong Sik Seo…·Paul Emile Bourgine
This study shows that aged human bone marrow mesenchymal stromal cells impair hematopoietic stem cell function under regeneration stress by promoting myeloid bias.
DOI 10.64898/2026.10.27.762262