Comparative spatial transcriptomics of hair follicle-T cell interactions in mouse, dog and human reveals conserved drivers of primary cicatricial alopecia
Ümmügülsüm Yıldız-Altay, Rutha Adhanom, Warda Abdi, Andrew Romasco, Lauren You, Nuha Salam, Robert Li, Haya S. Raef, Yuying Zhang, Elise Santacruz, Katelin Murphy, Saeed Shakiba, Mridushi Daga, Qi Tang, Matthew Olivera, , Jillian M. Richmond
This study uses spatial transcriptomics across mouse, dog, and human to identify conserved T cell-hair follicle interactions in PCA, revealing potential drug targets.
Nature Communications · Jul 27, 2026Peer-reviewedImmunology