Katherine Fleck

Developmental expression of the skeletal muscle determination gene, MyoD, is regulated by novel enhancer elements that interact with the core enhancer and distal regulatory region

The paper identifies novel enhancer elements that regulate MyoD expression during skeletal muscle development and show they are part of a cis-regulatory network.

Disentangling spatial organization and splicing of rare intron classes in the human genome

The paper investigates how spatial organization and splicing of rare intron classes are related in human cells, finding that intron identity, not position, primarily determines splicing efficiency.

Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease

The paper examines how the 3D genome landscape and disease influence the functional associations of human genes based on their evolutionary age and lineage restriction.