Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease
Katherine Fleck, Victor Luria, Nitanta Garag, Amir Karger, Trevor Hunter, Daniel Marten, William Phu, Kee-Myoung Nam, Nenad Šestan, A. H. O'Donnell-Luria, Jelena Erceg
The paper examines how the 3D genome landscape and disease influence the functional associations of human genes based on their evolutionary age and lineage restriction.
bioRxiv · Mar 17, 2024 · PreprintEvolutionary Biology