NeuroscienceStem Cell ReportsPeer-reviewed
Retinal ganglion cells harboring the OPTN(E50K) glaucoma mutation exhibit neurodegenerative phenotypes when derived from hPSC-derived three dimensional retinal organoids
Kirstin B. VanderWall, Kang-Chieh Huang, Yanling Pan…·Jason S. Meyer
This study shows that hPSC-derived RGCs with the OPTN(E50K) mutation display neurodegenerative phenotypes, providing insights into glaucoma mechanisms.
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