Author

Ken Lin

University of California, Santa BarbaraPrimary ORCID profile (0009-0007-5650-4303 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Ken LiniD1 paper · University of California Santa Barbara;

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1

Frequent Co-Authors

Aaron N. HataiD· 1 shared Anna E. MaciagiD· 1 shared Bin Wang· 1 shared Binh Khanh MaiiD· 1 shared Cathy ZhangiD· 1 shared Daniel AndrussieriD· 1 shared Emily Hensley· 1 shared Frank P. McCormickiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aaron N. HataORCID

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2 papers

Recent·Most cited

A binuclear copper enzyme platform for enantioconvergent radical (pseudo)halogenation

Xiao‐Wang Chen, Oluwatosin Maryam Adeyemo, Heyu Chen, Hongda Chen, Ngoc Nguyen, Joseph Palazzo, Liupeng Zhao, Ken Lin, Binh Khanh Mai, Peng Liu, Shiliang Tian, Yang Yang

This study reprograms binuclear copper enzymes to catalyze enantioselective radical (pseudo)halogenation reactions, demonstrating superior activity and selectivity compared to nonheme Fe enzymes.

bioRxiv · Sep 22, 2026 · PreprintBiochemistry

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRASG12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, Lauren Highfield, Jamie Wang, Emily Hensley, Grace Kelley, Sarah Clark, Michela Ranieri, Soumyadip Sahu, Cathy Zhang, Magdalena A. Ploszaj, Daniel Andrussier, Hsin‐Yi Huang, Ting Chen, , Aaron N. Hata

This study shows that a dual inhibitor of KRASG12C in both ON and OFF states more effectively suppresses tumor growth than an OFF-specific inhibitor by reducing PI3K-AKT activation.

bioRxiv · Apr 30, 2026 · PreprintCancer Biology