BiochemistrybioRxivPreprint
Basis for discrimination by engineered CRISPR/Cas9 enzymes
Mu-Sen Liu, Shanzhong Gong, Helen-Hong Yu…·David W. Taylor
This study investigates how engineered CRISPR/Cas9 variants improve off-target discrimination by analyzing their kinetic behavior during DNA cleavage.
DOI 10.1101/630509