Molecular BiologyMolecular and Cellular BiologyPeer-reviewed
Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects
Omar Hamdani, Namrita Dhillon, Tsung-Han S. Hsieh…·Rohinton T. Kamakaka
This study shows that removing tRNA genes from a chromosome does not broadly disrupt chromosome folding but affects local nucleosome positioning and SMC protein binding, as well as centromere and heterochromatin clustering.
30 citations