Author

Kimberly G. Malphrus

Mayo Clinic in Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Mariet AlleniD· 5 shared Nilüfer Ertekin‐TaneriD· 5 shared Thuy NguyeniD· 5 shared Xue WangiD· 5 shared Dennis W. DicksoniD· 4 shared Joseph S. ReddyiD· 4 shared Minerva M. CarrasquilloiD· 4 shared Zachary QuicksalliD· 4 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersNeuroscience

Mariet AllenORCID

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5 papers

Recent·Most cited

GeneticsMolecular NeurodegenerationPeer-reviewedJan 6, 2023

Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's Disease related proteins

Stephanie R. Oatman, Joseph S. Reddy, Zachary Quicksall…·Nilüfer Ertekin‐Taner

This study performs a genome-wide association study of brain biochemical phenotypes in Alzheimer's patients, identifying novel genetic loci and highlighting distinct genetic architectures for AD-related proteins.

24 citationstop 5%

humanproteomics

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NeurosciencebioRxivPreprintDec 28, 2021

Single Nuclei Transcriptome Reveals Perturbed Brain Vascular Molecules in Alzheimer's Disease

Özkan İş, Xue Wang, Tulsi Patel…·Nilüfer Ertekin‐Taner

The paper uses single nucleus RNA sequencing to analyze brain vascular cells in Alzheimer's disease, identifying molecular changes and interactions between vascular and astrocytic cells at the blood-brain barrier.

5 citations

humansnRNA-seq

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GeneticsbioRxivPreprintMay 13, 2021

Transcriptional landscape of human microglia reveals robust gene expression signatures that implicates age, sex and APOE-related immunometabolic pathway perturbations

Tulsi Patel, Troy Carnwath, Xue Wang…·Nilüfer Ertekin‐Taner

The paper characterizes human microglia transcriptomes and identifies gene expression signatures linked to age, sex, and APOE-ε4, revealing immunometabolic pathway perturbations in neurodegeneration.

DOI 10.1101/2021.05.13.444000

humanbulk RNA-seq

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NeurosciencebioRxivPreprintJan 18, 2021

Conserved Architecture of Brain Transcriptome Changes between Alzheimer's Disease and Progressive Supranuclear Palsy in Pathologically Affected and Unaffected Regions

Xue Wang, Mariet Allen, Joseph S. Reddy…·Nilüfer Ertekin‐Taner

2 citations

humanbulk RNA-seq

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NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 13, 2020

Deciphering cellular transcriptional alterations in Alzheimer's disease brains

Xue Wang, Mariet Allen, Shaoyu Li…·Nilüfer Ertekin‐Taner

The paper identifies cell-intrinsic differentially expressed genes in Alzheimer's disease by analyzing bulk-RNAseq data and comparing results to single nucleus RNAseq.

68 citations

humanbulk RNA-seq

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