Kristina W. Thiel

ASSET quantifies aptamer specificity in enriched libraries using NGS, enabling accurate classification of true and false positives in SELEX processes.

AptamerRunner clusters aptamers by sequence and structure to create visual networks for selecting high-quality candidates for experimental validation.

The paper describes an automated live-cell imaging method to assess drug responses in patient-derived organoid models, demonstrating its ability to quantify cell health and apoptosis over time.