Cancer BiologybioRxiv
KRASG12D and TP53R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus Scrofa Pigs
D. R. Principe, N. H. Overgaard, A. J. Park…·L. B. Schook
This study creates a transgenic pig model of pancreatic ductal adenocarcinoma by expressing KRASG12D and TP53R167H, showing tumor development in vivo and providing a new large animal model for research.
DOI 10.1038/s41598-018-30916-6